¹ý¶ûÁú Àΰø¿ì½Äº´¼Ò¿¡¼ APF gel°ú CPP-ACP Á¦Á¦ÀÇ Àç±¤È È¿°ú
REMINERALIZATION EFFECTS BY APF GEL AND CPP-ACP PASTE ON INCIPIENT ARTIFICIAL CARIES OF ENAMEL
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°Áö¼± ( Kang Ji-Sun ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
À̳¿µ ( Lee Nan-Young ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
ÀÌ»óÈ£ ( Lee Sang-Ho ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
KMID : 0358920080350040684
Abstract
¸¹Àº ¿¬±¸¿¡¼ ºÒ¼Ò ÀÌ¿ÂÀ» ÀÌ¿ëÇÑ Ä¡¾Æ¿ì½ÄÁõÀÇ ¿¹¹æ ¹× Àç±¤È È¿°ú¿¡ ´ëÇØ ¹àÈù ¹Ù ÀÖ´Ù. ºÒ¼Ò´Â Ä¡¾Æ¿ì½ÄÀ» ¿¹¹æÇÏ°í À籤ȸ¦ ÃËÁøÇÏ´Â ´ëÇ¥ÀûÀÎ ¼ººÐÀÌ´Ù. ÇÏÁö¸¸ ºÒ¼Ò¸¦ ÀÌ¿ëÇÑ À籤ȴ ÇϺÎÀÇ Å»È¸ º´¼Ò¸¦ ÃæºÐÈ÷ ±¤È½ÃÅ°Áö ¸øÇÏ¸ç ´Ù°ø¼ºÀ¸·Î ÀÎÇØ ºÒ¿ÏÀüÇÑ ±¤È¸¦ º¸ÀδÙ. ¶ÇÇÑ ±× Àû¿ë °úÁ¤¿¡¼ °ú·®ÀÌ ¼·ÃëµÇ¾úÀ» °æ¿ì¿¡ ¹ß»ýÇÒ ¼ö ÀÖ´Â µ¶¼ºµµ °í·ÁÇØ¾ß ÇÑ´Ù. ÇÑÆí CPP-ACP(Casein Phosphopeptides-Amorphous Calcium Phosphate)´Â ÃʱâÀÇ ¿ì½Äº´¼Ò¸¦ Àç±¤È ½ÃÅ°¸ç ¿ìÀ¯ ´Ü¹éÁúÀÎ caseinÀ¸·ÎºÎÅÍ ÃßÃâÇÑ ¼ººÐÀ¸·Î ¼·ÃëµÇ¾îµµ ÀÎü¿¡ ¹«ÇØÇÏ´Ù. º» ¿¬±¸ÀÇ ¸ñÀûÀº APF gel°ú CPP-ACP Á¦Á¦ÀÇ Àç±¤È È¿°ú¸¦ ºñ±³ÇØ º¸°íÀÚ ÇÏ´Â °ÍÀÌ´Ù. º» ½ÇÇè¿¡¼´Â ¹ý¶ûÁú Àΰø¿ì½Ä º´¼Ò¿¡ Acidulated Phosphate Fluoride(APF) gel°ú CPP-ACP Á¦Á¦¸¦ °¢ µµÆ÷ ¹æ¹ý¿¡ µû¶ó Àû¿ëÇÏ¿´´Ù. 14ÀÏ ÈÄ, Ç¥¸é¹Ì¼¼°æµµ¸¦ ÃøÁ¤ÇÏ°í Æí±¤ Çö¹Ì°æ ÇÏ¿¡¼ Àç±¤È º´¼Ò¸¦ °üÂûÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù. 1. ½ÇÇè ÀüÈÄ Ç¥¸é¹Ì¼¼°æµµ¸¦ ÃøÁ¤ÇÏ¿© ºñ±³ÇÑ °á°ú, ¸ðµç ±º¿¡¼ ½ÇÇè ÈÄ¿¡ Ç¥¸é¹Ì¼¼°æµµ°¡ Áõ°¡ÇÏ¿´´Ù(P<0.05). 2. CPP-ACP Á¦Á¦¸¦ µµÆ÷ÇÑ ±º¿¡¼ ºÒ¼Ò¸¦ µµÆ÷ÇÑ ±º¿¡ ºñÇØ Ç¥¸é¹Ì¼¼°æµµ Áõ°¡ ÆøÀÌ À¯ÀÇÇÏ°Ô ÄÇ´Ù(P<0.05). 3. Æí±¤Çö¹Ì°æ ÇÏ¿¡¼ °üÂûÇÑ °á°ú ºÒ¼ÒµµÆ÷ ±ºÀº ºÒ±ÔÄ¢ÇÏ°í ¾ãÀº Àç±¤È ÃþÀ», CPP-ACP Á¦Á¦¸¦ µµÆ÷ÇÑ ±ºÀº ±ÕÀÏÇÏ°í µÎÅÍ¿î Àç±¤È ÃþÀ» º¸¿´´Ù.
Many operations have been carried out using the fluoride ion to prevent and reverse dental caries. It certainly encourages remineralization and also prevents dental caries. However, the remineralization developed by these means is superficial only leaving lower levels of demineralized lesion with a degree of porosity and incomplete mineralization. We must consider its toxic effects when it is ingested for overdose. The CPP-ACP paste is able to remineralize the incipient lesion and has no harmful effects when it is ingested, because it was made form casein which is from the protein of milk. The purpose of this article is to compare the remineralization effects between APF gel and the CPP-ACP paste. we applicated the APF gel and CPP-ACP paste on the artificial enamel carious lesion. After 14 days, we measured the surface microhardness and observed the remineralized lesion under polarized light microscope. The results were as follows : 1. The surface microhardness of group III was the highest, followed by group II, and I(p<0.05). 2. The surface microhardness of group III was significantly higher than those of group I, and II(p<0.05). 3. We could observe thin and irregular remineralization layer of group II, and regular and moderate remineralization layer of group III under polirized light microscope.
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À籤È; ¹Ì¼¼°æµµ; Æí±¤Çö¹Ì°æ
CPP-ACP; APF gel; Remineralization; Microhardness; Polarized light microscope
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